Researchers stripped a virus of its infectious machinery and turned its benign core into a delivery vehicle that can target sick cells while leaving healthy tissue alone.
Stanford researchers have ripped the guts out of a virus and totally redesigned its core to repurpose its infectious capabilities into a safe vehicle for delivering vaccines and therapies directly where they are needed.
The study reported today in Proceedings of the National Academy of Sciences breathes new life into the field of targeted delivery, the ongoing effort to fashion treatments that affect diseased areas but leave healthy tissue alone.
Last modified Mon, 28 Sep, 2015 at 10:09
Most sensors designed to measure head impacts in sports produce inaccurate data, Stanford bioengineers find
As scientists zero in on the skull motions that can cause concussions, David Camarillo's lab has found that many commercially available sensors worn by athletes to gather this data are prone to significant error.
Amid growing concern about sports-related concussions, some athletes are beginning to wear head-mounted sensors that gauge the speed and force of impacts they receive during competition. Scientists are still working on identifying baseline parameters for injury, but research suggests that certain skull motions can contribute to concussions, and constant in-game monitoring of those motions promises to help limit injuries.
Last modified Thu, 3 Sep, 2015 at 10:53
It typically takes a year to produce hydrocodone from plants, but Christina Smolke and colleagues have genetically modified yeast to make it in just a few days. The technique could improve access to medicines in impoverished nations, and later be used to develop treatments for other diseases.
For thousands of years, people have used yeast to ferment wine, brew beer and leaven bread.
Now researchers at Stanford have genetically engineered yeast to make painkilling medicines, a breakthrough that heralds a faster and potentially less expensive way to produce many different types of plant-based medicines.
Last modified Thu, 3 Sep, 2015 at 10:54
A blue glowing device the size of a peppercorn can activate neurons of the brain, spinal cord or limbs in mice and is powered wirelessly using the mouse's own body to transfer energy. Developed by a Stanford Bio-X team, the device is the first to deliver optogenetic nerve stimulation in a fully implantable format.
A miniature device that combines optogenetics – using light to control the activity of the brain – with a newly developed technique for wirelessly powering implanted devices is the first fully internal method of delivering optogenetics.
The device dramatically expands the scope of research that can be carried out through optogenetics to include experiments involving mice in enclosed spaces or interacting freely with other animals. The work is published in the Aug. 17 edition of Nature Methods.
Last modified Thu, 3 Sep, 2015 at 10:53
Mounting evidence suggests that concussions in football are caused by the sudden rotation of the skull. David Camarillo's lab at Stanford has evidence that suggests current football helmet tests don't account for these movements.
When modern football helmets were introduced, they all but eliminated traumatic skull fractures caused by blunt force impacts. Mounting evidence, however, suggests that concussions are caused by a different type of head motion, namely brain and skull rotation.
Now, a group of Stanford engineers has produced a collection of results that suggest that current helmet-testing equipment and techniques are not optimized for evaluating these additional injury-causing elements.
Last modified Mon, 20 Jul, 2015 at 12:16
Thursday, August 13, 2015
Li Ka Shing, Room 120
Last modified Fri, 10 Jul, 2015 at 10:47
Manu Prakash, an assistant professor of bioengineering at Stanford, and his students have developed a synchronous computer that operates using the unique physics of moving water droplets. Their goal is to design a new class of computers that can precisely control and manipulate physical matter.
Computers and water typically don't mix, but in Manu Prakash's lab, the two are one and the same. Prakash, an assistant professor of bioengineering at Stanford, and his students have built a synchronous computer that operates using the unique physics of moving water droplets.
Last modified Thu, 11 Jun, 2015 at 10:17
Through special environments called biotic processing units, bioengineers let people interact with cells like fish in an aquarium or even do simple experiments from afar.
In the 1950s, computers were giant machines that filled buildings and served a variety of arcane functions. Today they fit into our pockets or backpacks, and help us work, communicate and play.
Last modified Tue, 21 Apr, 2015 at 9:25
The bioengineer and psychiatrist will be honored for his seminal role in the field of optogenetics, which allows scientists to precisely manipulate nerve-cell activity in freely moving animals to study their behavior.
Professor Karl Deisseroth will receive the Albany Medical Center Prize in Medicine and Biomedical Research for his pioneering work in optogenetics.
Last modified Mon, 20 Apr, 2015 at 11:40
Researchers from academia, industry and government launch effort to define standards for using bits and pieces of molecular biomachinery to create things such as vaccines, drugs and biosensors.
Just as defining the meter, kilogram and second helped lay the foundation for modern commerce, new measures and standards are needed to fuel the growth of the 21st Century bioeconomy.
The desire to create these new metrics brought more than 100 researchers from academia, industry and government to Stanford University on March 31st to launch a consortium convened by the National Institute of Standards and Technology, or NIST.
Last modified Thu, 16 Apr, 2015 at 9:49