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Annelise E. Barron

Annelise E. Barron

Postdoc, UCSF/Chiron Corporation, Biomimetic & Bioorganic Chemistry (1997)
Postdoc, Soane BioSciences/ACLARA Biosciences Inc., Molecular Biotechnology (1996)
Ph.D., Univ. of California, Berkeley, Chemical Engineering (1995)
B.S., Univ. of Washington, Seattle, Chemical Engineering (1990)

My research interests are in three areas:

(1) Molecular and cellular biophysics of human innate immunity, with a focus on the pleiotropic roles of host defense peptides and amyloidogenic peptides in human health and disease, including infectious disease, cancer, and plaque diseases, with a particular focus at present on Alzheimer's Disease.

(2) Design, synthesis, and biophysical studies of sequence-controlled, biomimetic oligomers (synthetic peptide mimics) with helical structures, for biomedical and biomaterial applications (mimicry of lung surfactant proteins, antimicrobial and anticancer innate immune peptides).

(3) Design, synthesis, and testing/demonstration of novel strategies and water-soluble polymeric materials for capillary and microchip electrophoresis (DNA sequencing and genotyping); creation of polymer-biomolecule conjugates.